Tesamorelin is a synthetic 44-amino-acid analogue of human growth-hormone-releasing hormone (GHRH 1-44) bearing an N-terminal trans-3-hexenoyl modification that increases resistance to DPP-4 cleavage. Supplied as lyophilised research material.

How does tesamorelin interact with the GHRH receptor?

It binds the GHRH receptor, a class B1 GPCR expressed on pituitary somatotrophs, coupling to Gs and raising cAMP. In cell assays this is measured as cAMP accumulation; in pituitary-cell preparations, as growth-hormone release into the medium.

What experimental models and literature exist?

Cultured pituitary cells and GHRHR-transfected lines for receptor pharmacology, plus a clinical literature for the approved tesamorelin drug product in HIV-associated lipodystrophy — a body of work that concerns the medicine, not this research reagent.

How does Pure Helix verify this tesamorelin lot?

Each lot is released against a batch-specific certificate of analysis: identity by mass spectrometry (observed mass compared with the calculated monoisotopic/average mass), chromatographic purity by RP-HPLC reported as area percent at a stated wavelength, and quantity/appearance checks on the lyophilised cake. The certificate for the exact lot shipped is linked from the COA tab and the COA database.

Tesamorelin (GHRH(1-44) Analog)

A stabilized GHRH analog with the identity data to back it up.

Tesamorelin

20mg

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Batch-verifiedShips from U.S.Public COAResearch-grade

Form

Lyophilized powder

Storage & Handling

Store lyophilized at -20°C.

Ships from

United States

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SKU TSM20Lot PH260614View COA for this lot →

Quantity

1

Price

$119.99

$119.99 per vial

$80.01 away from free shipping$200+

Independent verification

Identity & purity per lot

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Ships from U.S.

Domestic logistics

Batch-specific COA

Retrievable by lot ID

By adding to cart, purchaser certifies the materials are being acquired solely for legitimate laboratory research purposes. Not for human or veterinary use.

Form

Lyophilized powder

Storage & Handling

Store lyophilized at -20°C.

Ships from

United States

GHRH receptor binding studiesSomatotroph downstream signaling

A stabilized GHRH analog with the identity data to back it up.

Tesamorelin is a stabilized 44-amino-acid analog of human growth hormone-releasing hormone (GHRH), N-terminally modified for improved plasma stability. Research applications include GHRH-receptor binding, GH-secretagogue comparison studies, and downstream cAMP / MAPK signaling in cultured somatotroph and pituitary-adenoma cell lines. Supplied as a sterile lyophilized powder for reconstitution. For laboratory research use only.

Compound identity

Tesamorelin (GHRH(1-44) Analog)

Peptide Hormone & Analog—A peptide that acts as a signalling hormone, or a structurally modified version of one designed to alter stability or receptor behaviour.

Formula

C₂₂₁H₃₆₆N₇₂O₆₇S

Form

Lyophilized powder

Available sizes

20mg

Reconstitution

Per researcher protocol

Storage & Handling

Store lyophilized at -20°C.

Ships from

United States

Intended use

Research use only

Research areas

GHRH receptor binding studies
Somatotroph downstream signaling

Why researchers choose Pure Helix

Independently verified for identity and purity on a batch-specific basis.
Certificates of analysis publicly accessible by lot ID — never averaged.
Sourced through qualified manufacturing partners and shipped from the United States.
Fast shipping, always tracked, shipped from the United States.

Every lot

Batch-specific certificate of analysis, retrievable by lot ID.

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Reference

Research and documentation

Tesamorelin molecular reference

Formula, mass, sequence and documented lots

Quality & testing methods

Identity, purity and net content methods used for every lot

How to read a certificate of analysis

Field-by-field walkthrough of a Pure Helix COA

Lot certificatesPH260614 Verify on Bioviridian