IGF-1 LR3 — molecular reference
IGF-1 LR3 is an 83-amino-acid analog of insulin-like growth factor-1 featuring an N-terminal 13-amino-acid extension and an Arg³ substitution. These modifications markedly reduce affinity for IGF-binding proteins while preserving IGF-1 receptor engagement, extending its effective half-life in cell-culture media. Researchers use it in cultured myoblast, hepatocyte, and cancer-cell models to interrogate IGF-1R activation and downstream PI3K / Akt / mTOR signaling. Supplied as a sterile lyophilized powder (1 mg) for reconstitution in bacteriostatic water. For laboratory research use only.
Molecular data
- Compound name
- IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1)
- Research classification
- Peptide Hormone & Analog
- Molecular formula
- C990H1528N262O300S7
- Average molecular mass
- 22125 g/mol(calculated from molecular formula)
- Research pathway
- Growth Hormone Axis
- Physical form
- Lyophilized powder
- Storage & handling
- Store lyophilized at -20°C. Protect from light.
- Available presentations
- 1mg
- Current status
- Backordered
Fields with no verifiable source are omitted rather than estimated. Where an average mass is marked as calculated, it is derived arithmetically from the molecular formula using IUPAC standard atomic weights, not measured.
Documented assay contexts
Contexts in which this compound is used as a reference material in published in-vitro work. These describe laboratory usage, not effects in any organism.
- IGF-1 receptor binding studies
- PI3K / Akt / mTOR signaling assays
- Myoblast and hepatocyte in-vitro models
Lot documentation
| Lot | Presentation | Purity | Certificate |
|---|---|---|---|
| PH260826 | 1mg | — | Testing in progress |