MOTS-c (Mitochondrial ORF of the 12S rRNA-c)
The mitochondrial-derived peptide reshaping how labs think about cellular energetics.
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The mitochondrial-derived peptide reshaping how labs think about cellular energetics.
MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA that functions as a metabolic regulator across nuclear and cytoplasmic compartments. It is used in cultured skeletal-muscle, hepatocyte, and adipocyte models to study AMPK-mediated signaling, glucose uptake, and folate-methionine cycle intermediates as a proxy for mitochondrial-nuclear cross-talk. Supplied as a lyophilized powder. Research use only.
- Mitochondrial-derived peptide research
- AMPK signaling assays
- Glucose uptake in myotube culture
- Independently verified for identity and purity on a batch-specific basis.
- Certificates of analysis publicly accessible by lot ID — never averaged.
- Sourced through qualified manufacturing partners and shipped from the United States.
- Fast shipping, always tracked, shipped from the United States.

