MOTS-c — molecular reference
MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA that functions as a metabolic regulator across nuclear and cytoplasmic compartments. It is used in cultured skeletal-muscle, hepatocyte, and adipocyte models to study AMPK-mediated signaling, glucose uptake, and folate-methionine cycle intermediates as a proxy for mitochondrial-nuclear cross-talk. Supplied as a lyophilized powder. Research use only.
Molecular data
- Compound name
- MOTS-c (Mitochondrial ORF of the 12S rRNA-c)
- Research classification
- Single Peptide
- Molecular formula
- C101H152N28O22S2
- Average molecular mass
- 2175 g/mol(calculated from molecular formula)
- Research pathway
- Cellular & Mitochondrial
- Physical form
- Lyophilized powder
- Storage & handling
- Store lyophilized at -20°C.
- Available presentations
- 10mg
- Current status
- In Stock
Fields with no verifiable source are omitted rather than estimated. Where an average mass is marked as calculated, it is derived arithmetically from the molecular formula using IUPAC standard atomic weights, not measured.
Documented assay contexts
Contexts in which this compound is used as a reference material in published in-vitro work. These describe laboratory usage, not effects in any organism.
- Mitochondrial-derived peptide research
- AMPK signaling assays
- Glucose uptake in myotube culture
Lot documentation
| Lot | Presentation | Purity | Certificate |
|---|---|---|---|
| PH260807 | 10mg | 99.53% | View certificate |