Retatrutide — molecular reference
Retatrutide is a synthetic 39-amino-acid peptide that engages three incretin-family receptors — GLP-1R, GIP-R, and the glucagon receptor — simultaneously. Research groups use it in receptor binding and downstream cAMP / β-arrestin recruitment assays to characterize the balanced pharmacology of tri-agonists relative to dual (GLP-1/GIP) and mono agonists. Its extended half-life analog design supports in-vitro stability and comparative potency work in cultured adipocyte and hepatocyte models. Supplied as a sterile lyophilized powder for reconstitution in bacteriostatic water. For laboratory research use only — not for human or veterinary use.
Molecular data
- Compound name
- Retatrutide (GLP-1 / GIP / Glucagon Triple Agonist)
- Also referenced as
- GLP-3
- Research classification
- Peptide Hormone & Analog
- Molecular formula
- C221H342N46O68
- Average molecular mass
- ≈ 4731 Da(published value)
- Research pathway
- Metabolic Pathway
- Physical form
- Lyophilized powder
- Storage & handling
- Store lyophilized at -20°C. Protect from light.
- Available presentations
- 10mg · 20mg · 30mg · 50mg
- Current status
- In Stock
Fields with no verifiable source are omitted rather than estimated. Where an average mass is marked as calculated, it is derived arithmetically from the molecular formula using IUPAC standard atomic weights, not measured.
Documented assay contexts
Contexts in which this compound is used as a reference material in published in-vitro work. These describe laboratory usage, not effects in any organism.
- GLP-1/GIP/glucagon receptor signaling
- cAMP downstream assays
- Metabolic pathway modeling
Lot documentation
| Lot | Presentation | Purity | Certificate |
|---|---|---|---|
| PH260501 | 10mg | 99.9% | View certificate |
| PH260502 | 20mg | 99.9% | View certificate |
| PH260503 | 30mg | 99.9% | View certificate |
| PH260806 | 50mg | — | Testing in progress |
Related Pure Helix research
- Retatrutide (GLP-1 / GIP / Glucagon Triple Agonist) — catalog listing and current lots
- Retatrutide research hub
- Retatrutide mechanism of action and triple receptor activity
- Retatrutide vs tirzepatide: a mechanism comparison
- Retatrutide molecular structure, formula and mass
- Retatrutide receptor targets: GIPR, GLP-1R and GCGR
- Retatrutide purity testing: how Pure Helix lots are analysed
- How to read a retatrutide certificate of analysis
- How Pure Helix analytical testing works